Fig. 3
From: Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2
Inhibition of PCV2-induced cell apoptosis by Cepharanthine or Curcumin. a and b After cells were infected with 104.4 TCID50 of PCV2 for 2 h, cells were treated with Cepharanthine, Curcumin or Ribavirin for 48 h. The apoptosis rate was evaluated by Annexin V/PI staining followed by flow cytometry. The data on the graph indicated the total number of cells at the late apoptosis of the right upper quadrant and the early apoptosis of the right lower quadrant. The results indicated apoptosis rates were significantly decreased in the treated group with Cepharanthine, Curcumin or Ribavirin Compared to the PCV2-infected group except the group of 0.005 mg/mL Curcumin (P < 0.05)