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Table 1 Statistical Analysis Results: Comparison of baseline to treatment and placebo, and between treatment and placebo for all outcome measures

From: Evaluation of acupuncture for the treatment of pain associated with naturally-occurring osteoarthritis in dogs: a prospective, randomized, placebo-controlled, blinded clinical trial

 

Baseline Mean (± SE)

Treatment

Treatment/Placebo Mean (± SE)

Tukey

p-value between baseline and treatment

Tukey

p-value between treatment and placebo

Bonferroni corrected F-test

%BWD

20.5 (± 0.74)

Acupuncture

20.8 (± 0.87)

0.73

0.96

0.58a

Placebo

21.0 (± 0.83)

0.55

PVF

40.3 (± 2.1)

Acupuncture

40.1 (± 2.7)

0.97

0.99

1

Placebo

40.6 (± 2.4)

0.94

VI

6.75 (± 0.41)

Acupuncture

6.53 (± 0.44)

0.09

0.95

1

Placebo

6.55 (± 0.38)

0.17

ASI PVF Contralateral

16.4 (± 2.8)

Acupuncture

15.2 (± 2.8)

0.31

0.96

1

Placebo

14.9 (± 3.0)

0.46

ASI PVF Ipsilateral

21.2 (± 1.9)

Acupuncture

22.4 (± 1.8)

0.54

0.99

1

Placebo

21.8 (± 1.6)

0.46

ASI PVF Diagonal

22.0 (± 2.0)

Acupuncture

23.7 (± 1.8)

0.35

0.94

1

Placebo

23.3 (± 1.3)

0.19

ASI VI Contralateral

16.0 (± 2.6)

Acupuncture

15.6 (± 2.9)

0.84

0.97

1

Placebo

15.6 (± 2.6)

0.94

ASI VI Ipsilateral

27.2 (± 1.6)

Acupuncture

27.0 (± 2.0)

0.92

0.93

1

Placebo

26.8 (± 1.7)

0.10

ASI VI Diagonal

26.9 (± 2.0)

Acupuncture

27.6 (± 2.0)

0.80

0.95

1

Placebo

27.4 (± 1.9)

0.61

Total ACb

1,065,154 (± 262,894)

Acupuncture

1,057,267 (± 241,479)

0.31

0.84

1

Placebo

1,137,379 (± 351,793)

0.67

AC Sedentary

8083 (± 152)

Acupuncture

8051 (± 138)

0.13

0.76

1

Placebo

8045 (± 165)

0.47

AC Light

1250 (± 61)

Acupuncture

1246 (± 61)

0.76

0.79

1

Placebo

1218 (± 70)

0.10

AC Moderate

813 (± 98)

Acupuncture

760 (± 81)

0.75

0.68

1

Placebo

775 (± 101)

0.99

SOS

9.76 (± 0.53)

Acupuncture

9.27 (± 0.50)

0.035*

0.14

0.58

Placebo

9.76 (± 0.54)

0.80

CBPI PSS

4.04 (± 0.29)

Acupuncture

3.34 (± 0.32)

0.008*

0.343

0.18

Placebo

3.60 (± 0.36)

0.213

CBPI PIS

4.67 (± 0.36)

Acupuncture

3.50 (± 0.36)

0.0001*

0.257

0.003*

Placebo

3.85 (± 0.42)

0.018*

CSOM

3.16 (± 0.11)

Acupuncture

2.66 (± 0.11)

0.0002*

0.035*

0.005*

Placebo

2.93 (± 0.13)

0.221

  1. *indicates evidence of a difference (based on p < 0.05; not considering Bonferoni adjustment)
  2. aBonferoni adjusted p-values are shown for all variables except BWD (primary response variable) where the raw unadjusted p-value is shown
  3. bTotal AC was log10 transformed to satisfy model assumptions, but summary statistics are shown on original scale