Fig. 4From: Collagen extract obtained from Nile tilapia (Oreochromis niloticus L.) skin accelerates wound healing in rat model via up regulating VEGF, bFGF, and α-SMA genes expressionImmunohistochemistry results of VEGF : Vascular endothelial growth factor and TGF-β1:Transforming growth factor β1. a Control group showed mild VEGF expression of within the endothelial cells of the granulation tissue (arrows). b Tilapia group showed marked increase VEGF expression of within the endothelial cells of the mature granulation tissue underlying the epidermis (arrows). c Control group showing mild expression of TGF-β1 within the endothelial cells of the granulation tissue (arrows). d Tilapia group showed marked TGF-β1 expression either within the endothelial cells of blood capillaries (arrow) or fibroblastic cells (arrowheads), X200, bar = 40 µmBack to article page