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Table 6 Experimental groups used to evaluate the safety of interchangeable use of oral and subcutaneous administration of robenacoxib in cats

From: Safety evaluation of the interchangeable use of robenacoxib in commercially-available tablets and solution for injection in cats

Group

Treatment

Multiples of MRDa

Target daily oral dose level (mg/kg)

Target daily subcutaneousdose level / dose volume(mg/kg) / (mL/kg)

Number of cats

Males

Females

1

Controlb

0

0

0 / 0.3

5

5

2

Robenacoxib

1X

≥ 2.4

2.0 / 0.1

4

4

3

Robenacoxib

2X

≥ 4.8

4.0 / 0.2

4

4

4

Robenacoxib

3X

≥ 7.2

6.0 / 0.3

4

4

  1. aMRD maximum recommended dose
  2. bTwo empty capsules orally, sterile saline subcutaneously