Table 1 Mean (range) actual robenacoxib dosages during oral administration periods
Group Number (Multiples of MRD) | Target Dose Level(mg/kg/day) | Male | Female | ||
|---|---|---|---|---|---|
(mg/kg/day) | % of target | (mg/kg/day) | % of target | ||
1 (0X) | Placebo | 0.00 | NA | 0.00 | NA |
2 (1X) | 2.4 | 3.8 (2.4-4.7) | 158 | 3.2 (2.4-4.7) | 133 |
3 (2X) | 4.8 | 6.0 (4.8-6.9) | 125 | 5.9 (4.9-7.1) | 124 |
4 (3X) | 7.2 | 8.6 (7.2-9.6) | 119 | 8.8 (7.2-10.0) | 122 |