Analysis | Upstream regulator | Molecule type | Activation Z-score | P-value |
---|---|---|---|---|
CKCS vs Normal | F2 | Peptidase | 1.503 | 2.2E-12 |
TNF | Cytokine | 1.892 | 2.18E-11 | |
AGT | Growth factor | 2.018 | 1.15E-10 | |
TGFB1 | Growth factor | 1.486 | 9.03E-10 | |
CKCS vs non-CKCS | MEF2C | Transcription regulator | −3.087 | 1.11E-09 |
MYOCD | Transcription regulator | −2.768 | 1.33E-07 | |
2,3 butanedione monoxime | Chemical drug | −1.4 | 3.71E-07 | |
DNMT3A | Enzyme | 1.667 | 6.27E-07 | |
All diseased vs Normal | NOTCH4 | Transcription regulator | 1.777 | 6.33E-10 |
MED28 | Other | −1.957 | 6.32E-09 | |
HEY1 | Transcription regulator | −1.547 | 2.61E-08 | |
MYCOD | Transcription regulator | 2.571 | 4.6E-08 |