Comparative transcriptomic profiling of myxomatous mitral valve disease in the cavalier King Charles spaniel

BMC Veterinary Research

Table 1 Metadata for valve samples analysed. Whitney gross pathology grade (0 normal to 4 very severe) was assigned independently by two of the authors (GRM and BMC).

Breed	Gender	Age	Whitney Grade
Normal
Cross-terrier	Male	2 yrs	0
Cross-terrier	Male	3 yrs	0
Beagle	Male	3 yrs	0
Cross-Staffordshire bull terrier	Male	3 yrs	0
Beagle	Female	4 yrs	0
Beagle	Male	4 yrs	0
Mean Age +/−S.E.	3.1 yrs. +/−0.35
Non-CKCS
Cross-English bull terrier	Female	10 yrs	3
West Highland white terrier	Male	10 yrs	3
Jack Russel terrier	Female	11 yrs	4
Border collie	Male	13 yrs	4
Border collie	Male	13 yrs	4
Mean Age +/−S.E.	11.4 yrs. +/−0.27
CKCS
	Male	12 yrs	3
	Male	11 yrs	3
	Male	12 yrs	3
	Female	10 yrs	3
	Male	16 yrs	4
	Female	12 yrs	4
Mean Age +/−S.E.	12.5 yrs.+/−0.33

There was no significant difference in age between the CKCS and non-CKCS group, but there was for both compared to normal group (P < 0.001)

ISSN: 1746-6148