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Table 4 Impact of aerosolization of liposomal chicken vaccinea, incorporating H9N2 and MG antigens in presence and absence of Echinacea extract (EE), on protection in challengedb broilers against respective colonization and infection by MG and H9N2

From: Evaluation in broilers of aerosolized nanoparticles vaccine encapsulating imuno-stimulant and antigens of avian influenza virus/Mycoplasma gallisepticum

Treatmentc

Mean Mycoplasma gallisepticum colony count At 35 d of age (CFU/tracheal swab)

Mean recovery % Of tracheal H9N2 at 35 d of age

1

(2.5 × 102)1

(27.0)1

2

(5.0 × 102)2

(42.0)2

3

(3.0 × 10)3

(3.0)3

4

(2.0 × 104)4

(86.0)4

5

(0.0)5

(0.0)5

6

(0.0)5

(0.0)5

  1. aVaccination and/or EE administration to broilers at 14 and 21 days of age
  2. bChallenge at 28 days of age with 4HA units/50 μl of each of H9N2 and MG
  3. cTRT 1 = Vaccine administration containing H9N2 and MG antigens and challenged; TRT 2 = EE administration only and challenged; TRT 3 = Vaccine administration containing H9N2, MG, EE, and challenged; TRT 4 = Only challenged (positive controls); TRT 5 = Vaccine administration containing H9N2, MG, EE, and deprived of challenge; TRT 6 = Deprived of antigens and EE, and of challenge (Negative Controls)
  4. 1-5Bracketed means in a column followed by different Arabic numerical - superscripts are significantly different (P < 0.05)
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BMC Veterinary Research

ISSN: 1746-6148

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