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Fig. 5 | BMC Veterinary Research

Fig. 5

From: Safety studies and viral shedding of intramuscular administration of oncolytic vaccinia virus TG6002 in healthy beagle dogs

Fig. 5

Study chart and sample collection for safety evaluation of TG6002 in dogs. The first part of the study was conducted using four dogs to determine the maximal tolerated dose of TG6002. The second part of the study included three new dogs that were injected with TG6002 at the maximal dose determined in the first part of the study. The dogs were given three intramuscular injections of TG6002 with one-week intervals between injections. Four days after each injection, 5-FC was orally administered for three days. Samples collections for virus detection, complete blood count and blood chemistry are indicated

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