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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Exogenous Jaagsiekte Sheep Retrovirus type 2 (exJSRV2) related to ovine pulmonary adenocarcinoma (OPA) in Romania: prevalence, anatomical forms, pathological description, immunophenotyping and virus identification

Fig. 2

Microscopical findings of OPA. a Cytological exam of pulmonary tumors showing multiple nest of cubical to polygonal epithelial cells, interpreted as type II alveolar cells, DQ stain; b Histological appearance of OPA-classical form: tubular type and c papillary type, H&E stain; d and e The microphotographs of classical OPA showing myxoid growths (white arrow) interspersed with neoplastic epithelial component (blue arrow), H&E stain; f Histological exam of atypical OPA showing a well-delimited neoplastic nodule, surrounded by fibrous tissue and infilammatory infiltrates (arrow), H&E stain; g Myxoma-like tumor without neoplastic epithelial component. The mass is multinodular (white arrow) and composed of spindle to stellates cells, and abundant extracellular matrix (the inset), H&E stain; h and i AB-PAS stained sections from myxoma-like nodules showing abundant, pale blue extracellular myxomatous matrix; the Goblet cells of bronchial lining epithelium are used as positive control for AB-PAS stain

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