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Table 2 Mutations of p53 genes in MD

From: Detection of p53 mutation and serum monitoring alert caused by Marek’s disease virus in poultry

  Mutation analysis
Sample Info Base mutation sites Amino acid mutationsSite from to Mutation area
NC ND ND  
MD (C) 611 T-C; 786 A-C; 828 C -G; 1026 A-G 204 Y A
329 E G
Core domain
C-terminal domain
MD (C) 786 A-C; 803 g-A; 828 C-G; 864 C-A 268 R H Core domain
MD (C) 786 A-C; 828 C-G; 864 C-A ND  
MD (C) 828 C-G; 864 C-A ND  
MD (C) 487 delete; 539 T-C; 653 T-C; 786 A-C; 828 C-G 163 Stop Core domain
MD (C) 828 C-G; 864 C-A   
MD (E) 631–677 delete; 864 C-A; 879 C-A; 1026 T-G 210 Stop Core domain
MD (E) 786 A-C; 828 C-G; 864 C-A ND  
MD (E) 651 g-A; 864 C-A; 879 C-A ND  
MD (E) 674 A-G; 786 A-C; 828 C-G; 864 C-A; 878 C-T; 1094 g-A 225 N S
293 T I
365 G D
Core domain
C-terminal domain
MD (E) 786 A-C; 828 C-G; 864 C-A ND  
MD (E) 651 g-A; 701 g-T; 804 C-T; 828 C-G; 864 C-A;
907 g-A
234 R L
303 V M
152 E Y
153 H Y
Core domain
C- terminal domain
  1. NC was SPF chicken without diseases; (E) was experimental chicken; (C) was clinical chicken