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Table 3 Putative FQ resistance mutations and mutation rate

From: The prevalence and mechanism of fluoroquinolone resistance in Escherichia coli isolated from swine farms in China

NO of isolates and DANO MIC (μg/mL) Topoisomerases and gyrase mutations Efflux-related mutations
gyrA parC parE marR acrR
13 (128); 2 (64); S83L, D87N None None None None
2 (128); 1 (64) S83L, D87N S80I None None None
5 (128); 3 (64) S83L, D87N S80I None G103S None
2 (128); 1 (32) S83L, D87N None None G103S None
2 (128); 1 (32); 2 (8) None S80I None G103S None
1 (128); 1 (64) S83L, D87N S80I I355T,L416F None None
1 (128) None S80I None G103S V29G
1 (64) S83L, D87Y S80I None G103S None
1 (64) S83L, D87H None None G103S None
1 (64) S83L, D87N None None D67N,G103S None
1 (32) S83L, D87Y S80I None None None
2 (32) S83L None None G103S None
1 (32) S83L None None None None
1 (32) S83L, D87G None None None None
1 (16) None S80I, E84K None None None
1 (16) None E84K None None None
1 (1) None S80I None None None
1 (32)1 (4); 1 (1) None None None G103S None
mutation rate 52.70% 28.38% 2.70% 35.14% 1.35%
  1. Note: DANO Danofloxacin, NO number