Impact of dietary zinc oxide nanoparticles on selected serum biomarkers, lipid peroxidation and tissue gene expression of antioxidant enzymes and cytokines in Japanese quail

Table 1 Effect of dietary ZnO-NPs supplementation on serum selected biochemical parameters in Japanese quails

Parameters	Dietary groups				SEM	P values
Parameters	Group 1	Group 2	Group 3	Group 4	SEM	P values
AST (U/L)	16.02	17.07	16.35	17.62	0.48	0.695
ALT (U/L)	38.25	35.05	34.42	32.72	0.93	0.206
Total Proteins (mmol/L)	0.459	0.487	0.456	0.469	0.15	0.713
Albumin (mmol/L)	0.173	0.171	0.185	0.186	0.20	0.618
Globulin (mmol/L)	0.241	0.285	0.226	0.240	0.50	0.589
TC (mmol/L)	5.28^a	5.00^a	4.90^a	4.50^b	0.24	0.014
TAG (mmol/L)	5.31^a	5.03^a	4.66^b	4.54^b	0.29	0.006
Zinc (µmol/L)	10.80^b	12.39^b	13.13^b	19.70^a	0.65	0.004

^a−c Means within a row not sharing a common superscript differ significantly with corresponding p value
Group 1: control; Group 2: ZnO-NPs 15 mg/kg diet; Group 3: ZnO-NPs 30 mg/kg diet; Group 4: ZnO-NPs 60 mg/kg diet
Abbreviations: ZnO-NPs zinc oxide Nano particles, SEM Standard error of mean, ALT alanine aminotransferase, AST aspartate aminotransferase, TC total cholesterol, TAG triacylglycerol

ISSN: 1746-6148