Fig. 1
From: Pseudocowpox virus infection in an American bison (Bison bison)
Gross and histopathological lesions of PPV infection in American bison. a, b Multiple raised keratinized nodules on the skin of ventral aspect of tail, perineum, caudoventral abdomen, udder, inguinal recesses, medial aspect of thighs and axilla. c, d Histopathological examination of the skin nodules. There is marked epidermal hyperplasia with parakeratotic hyperkeratosis and ballooning degeneration of keratinocytes within the stratum corneum and stratum spinosum. Multifocally, swollen keratinocytes contain eosinophilic intracytoplasmic inclusion bodies (white arrows)