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Table 1 Intensity of congestion, mean (± standard deviation) number of mast cells (per mm2), mean (± standard deviation) epithelial thickness of the dorsum and the ventral surface (in microns) and mean (± standard deviation) of the number of nucleoli organizing regions (NORs) in the epithelium of the dorsal and ventral surfaces of the tongue by study group and exposure time (n = 80)

From: Evaluation of buccal damage associated with acute inhalation exposure to 2,4-dichlorophenoxyacetic acid (2,4-D) in mice

Groups* Congestion Number of mast cells Epithelial thickness Number of NORs
mild moderate dorsum ventral surface dorsum ventral surface
SG 1D 5/5 (100%)a 0/5 (0%)a 51.20 (15.04)a 34.55 (9.86)a 22.44 (4.23)a 396.6 (3.78)a 394.2 (13.55)a
SG 2D 5/5 (100%)a 0/5 (0%)a 53.00 (8.65)a 27.85 (7.87)a 27.58 (9.28)a 398 (12.57)a 374 (11.00)a
SG 3D 5/5 (100%)a 0/5 (0%)a 57.4 (11.13)a 30.86 (2.76)a 28.50 (17.07)a 405.8 (20.27)a 378.8 (5.40)a
SG 8D 5/5 (100%)a 0/5 (0%)a 62.2 (14.86)a 27.71 (6.18)a 21.73 (1.99)a 425.4 (20.18)a 359.8 (5.76)a
LCG 1D 5/5 (100%)a 0/5 (0%)a 57.4 (15.72)a 35.11 (5.03)b 24.61 (6.84)a 487.2 (6.97)b 377.8 (10.18)a
LCG 2D 5/5 (100%)a 0/5 (0%)a 57 (16.30)a 28.88 (4.75)a 24.02 (1.80)a 479.6 (11.90)b 363.4 (10.35)a
LCG 3D 5/5 (100%)a 0/5 (0%)a 63.6 (11.55)a 33.61 (6.11)a 25.56 (5.81)a 474.6 (13.93)c 384.8 (5.97)a
LCG 8D 5/5 (100%)a 0/5 (0%)a 46.2 (10.48)a 36.70 (4.60)b 29.70 (6.21)a 467.6 (6.18)c 394.2 (9.88)a
MCG 1D 5/5 (100%)a 0/5 (0%)a 39.6 (12.03)b 35.52 (4.16)b 25.32 (5.44)a 517 (21.62)d 513.4 (4.21)b
MCG 2D 5/5 (100%)a 0/5 (0%)a 59.8 (14.13)a 37.21 (7.29)b 28.68 (4.54)a 508.4 (13.46)d 506.2 (11.54)b
MCG 3D 2/5 (40%)b 3/5 (60%)b 49.6 (10.82)a 36.20 (3.10)b 20.03 (3.03)a 506 (5.33)d 494 (11.00)b
MCG 8D 5/5 (100%)a 0/5 (0%)a 50.8 (17.20)a 31.98 (8.73)a 29.24 (5.01)a 467.6 (1.34)c 394.2 (19.29)a
HCG 1D 3/5 (60%)b 2/5 (40%)b 42.6 (15.63)b 24.07 (5.64)c 23.44 (8.22)a 405.6 (28.93)a 403.2 (22.86)c
HCG 2D 3/5 (60%)b 2/5 (40%)b 40.2 (5.27)b 30.81 (8.47)a 27.70 (6.42)a 461 (13.13)c 387.2 (21.56)a
HCG 3D 5/5 (100%)a 0/5 (0%)a 44 (12.18)b 38.41 (4.52)b 26.76 (3.52)a 444.8 (20.46)d 410 (27.16)c
HCG 8D 3/5 (60%)b 2/5 (40%)b 32.2 (12.98)b 35.97 (3.22)b 23.93 (5.22)a 466 (10.93)c 377.2 (11.71)a
  1. *Groups: SG saline group; LCG low 2,4-D concentration group; MCG middle 2,4-D concentration group; HCG high 2,4-D concentration group; 1D one nebulization; 2D two nebulizations; 3D three nebulizations; 8D eight days after three nebulizations. Different lowercase letters means p-value < 0.05, where: a ≠ b, c, d; b ≠ a, c, d; c ≠ a, b, d; and d ≠ a, b, c. Lowercase letters compare the groups at the same time and in the same column