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Table 1 Comparison of laboratory variables in control and chronic kidney disease dogs

From: Investigation on urinary and serum alpha klotho in dogs with chronic kidney disease

Laboratory Variable

Control

(n = 10)

All CKD

(n = 27)

Stage 1

(n = 8)

Stage 2

(n = 8)

Stage 3

(n = 7)

Stage 4

(n = 4)

UrKl/Cr

(pg/gCr)

13.16

(5.75–34.84)

5.85

(0.08–82.28)

12.32

(3.03–82.28)

13.57

(2.15-18.00)

0.81

(0.30–4.37)

3.98

(0.08–5.85)

Serum Klotho

(pg/mL)

132.25

(57.46-169.33)

59.13

(0.47-189.13)

78.32

(10.47-122.47)

30.14

(0.47–72.47)

19.8

(2.47–70.47)

127.47

(77.13-189.13)

SDMA

(µg/dL)

8

(5–13)

28

(8–74)

13.5

(8–17)

22.5

(18–31)

37

(34–47)

58.5

(52–74)

Creatinine

(mg/dL)

0.8

(0.6-1)

1.9

(0.7–11.1)

1.1

(0.7–1.3)

1.75

(1.5–2.3)

3

(1.8–4.2)

5

(3.8–11.1)

BUN

(mg/dL)

21.4

(9-33.8)

55.7

(6.8-167.7)

25.05

(6.8–47.5)

51.25

(19-108.2)

89

(43.4-111.8)

135.6

(76.7-167.7)

Phosphorus

(mg/dL)

3.7

(3.1–5.2)

3.9

(2.9–19)

3.3

(2.9–3.8)

4

(2.9–5.3)

5.9

(3.1–8.38)

11.15

(4.39-19)

  1. Results are presented as median and range.
  2. UrKl/Cr, urine klotho-to-creatinine ratio; SDMA, symmetric dimethylarginine; BUN, blood urea nitrogen.