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Table 1 Location within the skin, actinic changes and tumor size of canine cutaneous hemangiomas and hemangiosarcomas

From: Immunohistochemical detection of p53 and pp53 Ser392 in canine hemangiomas and hemangiosarcomas located in the skin

Cutaneous endothelial tumors

Location within the skin a

Actinic changes b

Tumor size c

Number of tumors/total tumors (percentage)

P value

Number of tumors/total tumors (percentage)

P value

Number of tumors/total tumors (percentage)

P value

Dermal

Hypodermal

No

Yes

≤5 cm

> 5 cm

Histological diagnosisd

  

.008

  

.001

  

.491

Hemangioma

0/13 (0%)

13/13 (100%)

 

11/12 (91.67%)

1/12 (8.33%)

 

10/11 (90.91%)

1/11 (9.09%)

 

Hemangiosarcoma

10/25 (40.0%)

15/25 (60.0%)

0/17 (0%)

17/17 (100%)

 

20/24 (83.33%)

4/24 (16.67%)

Histological differentiation scoringd

  

.667

  

  

1.000

Well-differentiated

4/8 (50.0%)

4/8 (50.0%)

 

0/6 (0%)

6/6 (100%)

 

8/9 (88.89%)

1/9 (11.11%)

 

Moderately differentiated

6/17 (35.29%)

11/17 (64.71%)

0/11 (0%)

11/11 (100%)

 

12/15 (80.0%)

3/15 (20.0%)

  1. Non-included in inferential statistical study the poorly differentiated hemangiosarcoma (case No. 40)
  2. a Unavailable data in 1 hemangiosarcoma (case No. 22)
  3. b Unavailable data in 1 hemangioma (case No. 2) and 9 hemangiosarcomas (cases Nos. 14, 16, 17, 24, 28, 31, 32, 36, and 37)
  4. c Unavailable data in 2 hemangiomas (cases Nos. 6 and 7) and 2 hemangiosarcomas (cases Nos. 28 and 29)
  5. d Fisher’s exact test