Skip to main content

Table 5 Flunixin and 5-hydroxyflunixin concentrations (ng/mL) in urine and oral fluids after intramuscular administration of flunixin meglumine at 2.2 mg/kg in finishing-age swine

From: A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing-age swine

Group

Pig ID

Urine

Pen-Level Oral Fluids

Flunixin

5-hydroxyflunixin

Flunixin

5-hydroxyflunixin

G1

(Day 1)

260

9459.1

1295.0

168.6

21.0

261

3762.5

972.0

270 (C)

231.4

16.5

273

3032.0

724.4

G2

(Day 4)

262

60.3

<LOQ

16.8

10.9

264

22.7

<LOQ

269

35.5

<LOQ

274 (C)

11.6

<LOQ

G3

(Day 8)

258

<LOQ

<LOQ

<LOQ

<LOQ

266 (C)

<LOQ

NF

268

<LOQ

NF

272

<LOQ

NF

G4

(Day 12)

263

NF

NF

12.3

11.3

267

<LOQ

NF

271

<LOQ

NF

275 (C)

<LOQ

NF

G5

(Day 16)

257

NF

NF

<LOQ

10.6

259

NF

NF

265 (C)

NF

NF

276

NF

NF

  1. Note: Oral fluids were a group sample from all four pigs in the group at the day of necropsy. Concentrations that were below the level of quantification (LOQ) were designated “LOQ”. For this assay the LOQ was 5 ng/mL. If no flunixin or 5-hydroxyflunixin levels were detected, the sample was designated “NF”. Untreated, control pigs used to assess the potential for environmental contamination were designated (C)