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Table 8 Histopathological assessment of dietary agrimos® supplementation on E. coli challenged broiler chicken ((n = 10)

From: Impact of dietary Mannan-oligosaccharide and β-Glucan supplementation on growth, histopathology, E-coli colonization and hepatic transcripts of TNF-α and NF- ϰB of broiler challenged with E. coli O78

Lesions

Infected group

Agrimos non-infected group

Agrimos infected group

At 15 days

At 35 days

At 15 days

At 35 days

At 15 days

At 35 days

B

T

S

B

T

S

B

T

S

B

T

S

B

T

S

B

T

S

Sub capsular heterophilic aggregation

 

Normal

 

Normal

Normal

Normal

Normal

Normal

Normal

Normal

Normal

Normal

 

Normal

Sub and interstitial edema

 

 

+

+

 

Interstitial hemorrhages

 

 

+

 

Interstitial connective tissue proliferation

 

 

 

Epithelial folding and lobulation

+

 

 

 

Epithelial hyperplasia

+

 

+

 

+

+

 

Epithelial degeneration and/or necrosis

+

 

+

 

+

 

Reduction in size and numbers of follicles

 

 

 

Follicular atrophy or cortical atrophy

 

+

+

+

Follicular cyst and necrosis

 

 

+

 

Lymphocytic depletion

 

 

+

 

Appearance of holes in medulla

+

++

 

Reticular cells proliferation

 

 

 

Vasculitis

 

 

 

Cortical necrosis

 

 

 

Apoptotic bodies and/or karyorhexis

+

 

 

Hyalinization and thrombosis of blood vessels

 

 

 
  1. +++ Sever ++ Moderate + Mild B = Bursa T = Thymus S=Spleen