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Fig. 1 | BMC Veterinary Research

Fig. 1

From: Ultrastructural changes in endothelial cells of buffaloes following in-vitro exposure to Pasteurella multocida B:2

Fig. 1

Ultrastructural changes in BAEC exposed to P. multocida B:2. a Severe nuclear invagination (long arrow), with dilatation, fragmentation, and vesiculation of RER (short arrows). Few mitochondria had cristae disarrangement and partial cristolysis (arrowhead), with low number of P. multocida B:2 (asterisk) in the cytoplasm. (bar = 2 μm, TEM). b Disintegration of plasma membrane and nuclear envelope (long arrows), with prominent swollen mitochondria and cristae disarrangement (short arrow) and RER vesiculation (arrow head) (bar = 2 μm, TEM). c Presence of numerous P. multocida B:2 (asterisks) inside and outside of a lysed BAEC (long arrow). Mitochondria cristolysis (short arrow) and ribosomal degranulation from RER membranes with accumulation of ribosomal fragments in the cytosol were also noted (arrow heads) (bar = 2 μm, TEM). d. Presence of lysed (long arrow) and intact (short arrows) P. multocida B:2 with shedding of outer membrane (arrowheads). (bar = 500 nm, TEM)

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