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Table 2 List of upregulated genes related to ECM

From: Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis

ECM proteins log2 fold changeFDR
COL5A3Collagen type V alpha 3 chain4.15986.87E-06
COL18A1Collagen type XVIII alpha 1 chain3.55315.90E-06
COL15A1Collagen type XV alpha 1 chain3.46613.79E-06
COL1A1Collagen alpha-1(I) chain3.22257.54E-05
COL3A1Collagen type III alpha 1 chain3.18392.31E-05
COL16A1Collagen type XVI alpha 1 chain2.83781.37E-05
COL27A1Collagen type XXVII alpha 1 chain2.60610.0001001
COL5A2Collagen type V alpha 2 chain2.59051.21E-05
COL6A3Collagen type VI alpha 3 chain2.40470.00016717
COL6A2Collagen type VI alpha 2 chain2.35390.00022812
COL24A1Collagen type XXIV alpha 1 chain2.16129.72E-05
COL6A1Collagen type VI alpha 1 chain2.12720.0003894
COL4A2Collagen type IV alpha 2 chain1.70880.00033908
POSTNPeriostin6.74281.01E-07
SPP1Secreted phosphoprotein 1;Osteopontin4.62412.73E-05
LAMA4Laminin subunit alpha 43.77451.58E-09
LAMB4laminin subunit beta-42.12444.93E-05
FN1Fibronectin2.73272.75E-06
LAMC2Laminin subunit gamma 22.40190.00041187
ECM binding proteinlog2 fold changeFDR
LUMLumican4.94970.00013751
ITGA2Integrin subunit alpha 23.11840.00031867
ITGA6Integrin subunit alpha 62.34564.69E-05
DDR2Discoidin domain receptor tyrosine kinase 22.18740.00011485
BGNBiglycan2.17030.00022031
ITGA5Integrin subunit alpha 51.99461.61E-06
PDPN*Podoplanin3.61716.43E-05
ECM related enzymelog2 fold changeFDR
ADAMTS14ADAM metallopeptidase with thrombospondin type 1 motif 143.50271.30E-08
ADAM12ADAM metallopeptidase domain 123.00331.90E-10
TLL1Metalloendopeptidase3.21160.00023572
ADAMTS4ADAM metallopeptidase with thrombospondin type 1 motif 42.75260.00018318
TIMP1Metalloproteinase inhibitor 12.43160.00021979
P4HA2Prolyl 4-hydroxylase subunit alpha 21.72592.73E-06
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxtgenase 11.68270.0001534
MMP14Matrix metalloproteinase1.67846.43E-07