Fig. 2

Mean layer thicknesses with age of REC+, ONL, IS/OS and heat map in the AC.a-c. Mean (+/− SD) layer thicknesses with age of a. Receptor+ (REC+), b. Outer nuclear layer (ONL), c. Photoreceptor inner segment/outer segment (IS/OS) for the 5 regions. Note that in the dorsal, ventral, nasal and temporal regions the REC+ thinned with age. In the area centralis it was thinner than in the other regions and trended towards thickening with age (A). The ONL in the area centralis changed little with age (whereas in the other areas in thinned). The change in REC+ thickness with age in the area centralis seemed to be accounted for primarily by thickening of the IS/OS. d, e. Heat maps showing layer thickness of ONL and IS/OS in the region of and surrounding the area centralis in a 12-week-old dog. This shows the regionality of the difference in thickness of these 2 layers