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Table 2 Differences in hemolysin gene transcription activities between weakly hemolytic B. hyodysenteriae strain G423 and strongly hemolytic strain B204 determined with the software REST®

From: Differential expression of hemolysin genes in weakly and strongly hemolytic Brachyspira hyodysenteriae strains

Hemolysin gene Relative expression report of G423 (control strain) compared with B204 (sample strain) determined by the software REST®
Time point 1 Time point 2 Time point 3 Time point 4
Expression p-value Result Expression p-value Result Expression p-value Result Expression p-value Resulta
tlyA 1.191 0.795   21.148 0.004 UP 1.403 0.549   0.919 0.881  
tlyB 0.490 0.003 DOWN 1.493 0.413   0.168 0.000 DOWN 1.489 0.103  
tlyC 1.698 0.380   6.815 0.040 UP 0.288 0.042 DOWN 0.894 0.807  
hlyA 0.257 0.146   0.617 0.250   0.035 0.000 DOWN 0.573 0.143  
hemolysin III 2.799 0.041 UP 6.269 0.004 UP 0.743 0.485   0.350 0.001 DOWN
hemolysin activa-tion protein gene 0.378 0.372   1.234 0.599   2.110 0.050 UP 2.054 0.011 UP
hemolysin channel protein gene 0.927 0.873   1.501 0.240   0.490 0.001 DOWN 1.542 0.010 UP
hemolysin gene 22.245 0.000 UP 6.088 0.004 UP 1.596 0.173   1.668 0.412  
  1. aDOWN = hemolysin gene is downregulated in B204 in comparison with G423 by the mean factor described in the field “expression”, UP = hemolysin gene is upregulated in B204 in comparison with G423 by the mean factor described in the field “expression”