Pharmacokinetics and analgesic effects of intravenous, intramuscular or subcutaneous buprenorphine in dogs undergoing ovariohysterectomy: a randomized, prospective, masked, clinical trial

Table 1 Demographic data, doses of propofol, duration of anesthesia and surgery and length of incision in dogs undergoing ovariohysterectomy and administered buprenorphine (Simbadol; 0.02 mg/kg) by the intravenous (IV), intramuscular (IM) or subcutaneous (SC) routes of administration

Variables	IV n = 8	IM n = 8	SC n = 8	p value
Body condition score (1–9)	5 (5–8)	5 (4–7)	5 (4–7)	0.4127
Body weight (kg)	22.4 ± 9.6	19.0 ± 4.3	18.2 ± 7.2	0.4921
Age (year)	4.6 ± 2.5^a	2.9 ± 2.4	1.7 ± 1.8^b	0.0489
Propofol (mg/kg)	4.2 ± 0.8^a	4.6 ± 0.7	5.3 ± 1.0^b	0.0478
Duration of anesthesia (minutes)	52.6 ± 9.7	47.4 ± 8.6	44.3 ± 6.8	0.1597
Duration of surgery (minutes)	33.9 ± 8.8	30.3 ± 6.7	26.6 ± 3.9	0.1280
Time to extubation (minutes)	3.1 ± 1.6	2.4 ± 1.1	2.3 ± 0.9	0.3087
Length of incision (cm)	3.9 ± 1.4	4.1 ± 1.3	3.6 ± 1.0	0.7093

Data are presented as mean ± standard deviation or as mean (range) where appropriate. The p values refer to the comparisons among the three groups. Different superscript letters indicate significant difference between groups. Values of p < 0.05 were considered significant (italics)

ISSN: 1746-6148