Boxplots comparing the mean transit time (MTT -- a), the cerebral blood flow (CBF -- b) and the cerebral blood volume (CBV -- c) for five different regions of interests (ROIs) between diseased and healthy dogs. All values are normalized with respect to the Centrum semiovale and were computed using a choice of alpha = 0.3. We clearly see a tendency of a higher mean transit time and a lower cerebral blood flow for diseased dogs, most prominently for the Hippocampus and the Thalamus. The box represents the interquartile range of the respective value, with the median value been shown as a vertical line within the box. The whiskers show the lower and upper extreme. The single data points represent the outliners. For example, in Fig. 4a, the box shows the interquartile range for the MTT for different regions named in the top row of each individual graph for diseased and healthy dogs.