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Table 1 Virulence of rSC0012(pS-SaoA) in 3-week-old BALB/c mice

From: Live-attenuated Salmonella enterica serotype Choleraesuis vaccine with regulated delayed fur mutation confer protection against Streptococcus suis in mice

StrainDescriptionLD50 (CFU)
Orali.p
C78–3Wild type9.5 × 102< 10
rSC0018(pS-SaoA)ΔasdA33 in a live attenuated S. Choleraesuis vaccine strain C500> 2.8 × 1096.6 × 106 **, ##
rSC0012(pS-SaoA)ΔPfur88::TT araC PBADfur Δpmi-2426 ΔrelA199::araC PBADlacI TT ΔasdA33 in C78–3> 5.8 × 109**2.1 × 107 **, ##
rSC0011(pS-SaoA)ΔPcrp527::TT araC PBADcrp Δpmi-2426 ΔrelA199::araC PBADlacI TT ΔasdA33 in C78–3> 1.0 × 109**5.4 × 105 **
  1. **, P < 0.01, compared with C78–3; ##, P < 0.01, compared with rSC0011 (pS-SaoA)