Fig. 6
Induction of inflammatory cytokines at 6 h and 12 h post-infection in ten mice immunized with different Salmonella strains. Analysis of RNA transcript levels by qPCR showed that all mutant strains induced less inflammatory cytokine production than the wild-type strain C78-3 at both 6 h (a and c) and 12 h (b and d) post-infection. &, P < 0.05, C78-3 ΔPfur88 TT araC PBADfur compared to C78-3; #, P < 0.05, ##, P < 0.01, rSC0012(pS-SaoA) compared to rSC0011(pS-SaoA); *, P <0.05, **, P < 0.01, strains with ΔPfur88 TT araC PBADfur mutation compared to C78-3