Fig. 4From: Live-attenuated Salmonella enterica serotype Choleraesuis vaccine with regulated delayed fur mutation confer protection against Streptococcus suis in miceAntibody responses in ten mice. Serum IgG responses to SaoA (a), S. Choleraesuis OMPs (b) and vaginal wash IgA responses to SaoA (c) were measured by ELISA at weeks 3 and 5. Each triangle represents one mouse. Error bars represent variation between mice. Significant differences were indicated. *, P < 0.05; ** P < 0.01, for Salmonella carrying pS-SaoA compared to each other; #, P < 0.05; ##, P < 0.01, for the titers of antibody at 3 weeks after immunization were compared to those at 5 weeks after immunization. No immune responses were detected to antigen tested in mice immunized with PBS or in pre-immune sera from vaccinated mice (reciprocal titer <1:50). The assay was performed in duplicate and repeated at least 3 timesBack to article page