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Fig. 4 | BMC Veterinary Research

Fig. 4

From: Live-attenuated Salmonella enterica serotype Choleraesuis vaccine with regulated delayed fur mutation confer protection against Streptococcus suis in mice

Fig. 4

Antibody responses in ten mice. Serum IgG responses to SaoA (a), S. Choleraesuis OMPs (b) and vaginal wash IgA responses to SaoA (c) were measured by ELISA at weeks 3 and 5. Each triangle represents one mouse. Error bars represent variation between mice. Significant differences were indicated. *, P < 0.05; ** P < 0.01, for Salmonella carrying pS-SaoA compared to each other; #, P < 0.05; ##, P < 0.01, for the titers of antibody at 3 weeks after immunization were compared to those at 5 weeks after immunization. No immune responses were detected to antigen tested in mice immunized with PBS or in pre-immune sera from vaccinated mice (reciprocal titer <1:50). The assay was performed in duplicate and repeated at least 3 times

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