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Table 1 Serum AA evaluation in dogs with IRE vs CD

From: Serum amino acid profile in 51 dogs with immunosuppressant-responsive enteropathy (IRE): a pilot study on clinical aspects and outcomes

Amino acid (nmol/mL)

CD (26 dogs)

IRE (51 dogs)

p-value

AABAb

34.63 ± 12.99

45.77 ± 15.89

0.06

ALAa

93.70 (56.57–225.9)

99.96 (14.23–334.1)

0.62

ARGa

57.80 (11.43–172.5)

84.54 (20.10–149.8)

< 0.001

ASPa

1.28 (0.16–5.46)

1.87 (0.21–12.08)

0.17

CYSb

39.90 ± 14.66

52.47 ± 18.22

0.003

GLUa

8.77 (4.38–20.55)

20.63 (4.32–67.85)

0.001

GLYa

48.44 (4.75–84.35)

48.92 (12.10–131.9)

0.64

HISa

198.9 (24.9–323.4)

191.3 (21.3–326.9)

0.46

ILEa

23.84 (12.69–45.43)

29.94 (2.82–69.45)

0.005

LEUa

10.55 (7.76–19.40)

11.67 (1.77–20.18)

0.23

LYSa

7.16 (3.79–32.67)

9.56 (1.26–23.82)

0.018

METa

4.77 (0.32–58.49)

5.96 (0.14–12.81)

0.21

PHEb

12.60 ± 5.24

7.73 ± 3.24

< 0.001

PROa

6.15 (3.9–34.84)

11.02 (0.7–29.76)

0.044

SERa

35.50 (23–69.79)

45.01 (7.24–160)

0.02

THRa

48.78 (30.45–99.66)

68.29 (14.77–154.5)

0.013

TRPa

47.77 (19.68–108.3)

30.18 (10.24–70.18)

< 0.001

TYRa

11.15 (6.29–48.48)

7.87 (0.18–30.92)

< 0.001

VALa

4.88 (2.96–12.68)

6.22 (0.64–62.49)

0.018

  1. CD control group, IRE immunosuppressant responsive enteropathy, AABA L-Amino-n-butyric acid ALA Alanine, ARG L-Arginine, ASP L-Aspartic acid, CYS L-Cysteine, GLU L-Glutamic acid, GLY Glycine, HIS L-Histidine, ILE L-Isoleucine, LEU L-Leucine, LYS L-Lysine, MET L-Methionine, PHE L-Phenylalanine, PRO Proline, SER L-Serine, THR L-Threonine, TRP Tryptophan, TYR L-Tyrosine, VAL L-Valine. Non-parametric data are expressed as median and minimum and maximum in brackets and the respective p-values were obtained using Mann-Whitney U-test (a), while parametric data are expressed as mean ± standard deviation and respective p-values were obtained using unpaired t-test (b)