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Table 1 Serum AA evaluation in dogs with IRE vs CD

From: Serum amino acid profile in 51 dogs with immunosuppressant-responsive enteropathy (IRE): a pilot study on clinical aspects and outcomes

Amino acid (nmol/mL)CD (26 dogs)IRE (51 dogs)p-value
AABAb34.63 ± 12.9945.77 ± 15.890.06
ALAa93.70 (56.57–225.9)99.96 (14.23–334.1)0.62
ARGa57.80 (11.43–172.5)84.54 (20.10–149.8)< 0.001
ASPa1.28 (0.16–5.46)1.87 (0.21–12.08)0.17
CYSb39.90 ± 14.6652.47 ± 18.220.003
GLUa8.77 (4.38–20.55)20.63 (4.32–67.85)0.001
GLYa48.44 (4.75–84.35)48.92 (12.10–131.9)0.64
HISa198.9 (24.9–323.4)191.3 (21.3–326.9)0.46
ILEa23.84 (12.69–45.43)29.94 (2.82–69.45)0.005
LEUa10.55 (7.76–19.40)11.67 (1.77–20.18)0.23
LYSa7.16 (3.79–32.67)9.56 (1.26–23.82)0.018
METa4.77 (0.32–58.49)5.96 (0.14–12.81)0.21
PHEb12.60 ± 5.247.73 ± 3.24< 0.001
PROa6.15 (3.9–34.84)11.02 (0.7–29.76)0.044
SERa35.50 (23–69.79)45.01 (7.24–160)0.02
THRa48.78 (30.45–99.66)68.29 (14.77–154.5)0.013
TRPa47.77 (19.68–108.3)30.18 (10.24–70.18)< 0.001
TYRa11.15 (6.29–48.48)7.87 (0.18–30.92)< 0.001
VALa4.88 (2.96–12.68)6.22 (0.64–62.49)0.018
  1. CD control group, IRE immunosuppressant responsive enteropathy, AABA L-Amino-n-butyric acid ALA Alanine, ARG L-Arginine, ASP L-Aspartic acid, CYS L-Cysteine, GLU L-Glutamic acid, GLY Glycine, HIS L-Histidine, ILE L-Isoleucine, LEU L-Leucine, LYS L-Lysine, MET L-Methionine, PHE L-Phenylalanine, PRO Proline, SER L-Serine, THR L-Threonine, TRP Tryptophan, TYR L-Tyrosine, VAL L-Valine. Non-parametric data are expressed as median and minimum and maximum in brackets and the respective p-values were obtained using Mann-Whitney U-test (a), while parametric data are expressed as mean ± standard deviation and respective p-values were obtained using unpaired t-test (b)