Table 2 Voriconazole concentrations in the different ocular tissues for the 3 timepoints. The data for the 2 h and 48 h timepoints were from opposite eyes from the same 3 horses

Cornea

Dorsal

4.43/3.90

2.17/2.58–6.82

5.04/3.15

3.83/2.52–9.45

0.33/0.00

0.33/0.00–1.00

Ventral

3.01/3.19

1.28/1.65–4.19

1.91/1.20

1.37/1.03–3.49

0.38/0.41

0.14/0.12–0.62

Aqueous humor

Dorsal

0.14/0.10

0.03/0.06–0.15

0.61/0.61

0.15/0.46–0.76

0.30/0.28

0.06/0.20–0.41

Ventral

1.56/1.23

0.66/1.12–2.32

0.58/0.52

0.13/0.49–0.73

0.10/0.11

0.06/0.00–0.19

Lens

Dorsal

0.19/0.16

0.17/0.03–0.37

0.30/0.34

0.12/0.16–0.40

0.07/0.11

0.04/0.00–0.11

Ventral

0.11/0.11

0.05/0.06–0.16

0.13/0.18

0.10/0.01–0.19

0.17/0.14

0.04/0.13–0.24

Iris

Dorsal

1.41/1.18

0.78/0.78–2.28

2.03/1.41

1.43/1.02–3.67

0.26/0.11

0.21/0.00–0.68

Ventral

0.39/0.43

0.08/0.29–0.44

0.72/0.63

0.20/0.59–0.95

0.26/0.10

0.17/0.08–0.61

Sclera

Dorsal

5.69/3.68

4.68/2.35–11.04

7.35/4.88

6.03/2.95–14.22

0.11/0.00

0.11/0.00–0.33

Ventral

0.12/0.12

0.07/0.06–0.19

1.83/1.14

1.28/1.04–3.30

0.01/0.00

0.01/0.00–0.03

Choroid

Dorsal

0.66/0.68

0.42/0.23–1.07

0.81/0.78

0.18/0.64–1.00

0.50/0.16

0.42/0.00–1.33

Ventral

0.94/0.99

0.20/0.72–1.11

0.66/0.68

0.08/0.58–0.73

0.18/0.00

0.18/0.00–0.54

Retina

Dorsal

0.89/0.63

0.65/0.40–1.63

0.35/0.39

0.08/0.26–0.41

0.15/0.20

0.08/0.00–0.26

Ventral

0.33/0.28

0.15/0.22–0.50

0.22/0.24

0.10/0.12–0.31

0.08/0.09

0.05/0.00–0.16

Vitreous

Dorsal

0.03/0.02

0.03/0.01–0.00

0.02/0.01

0.01/0.01–0.03

0.00/0.00

0.00/0.00–0.01

Ventral

0.10/0.01

0.15/0.01–0.27

0.02/0.01

0.01/0.01–0.03

0.01/0.01

0.01/0.00–0.02