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Table 1 Voriconazole concentration in tears and aqueous humor for the voriconazole thermogel (Vori-Gel) and topical voriconazole (Vori-Top) groups, n = 6

From: Sustained-release voriconazole-thermogel for subconjunctival injection in horses: ocular toxicity and in-vivo studies

 

Day

Mean (μg/mL)

SD

Median (μg/mL)

Range

Vori-Gel (1.7% voriconazole thermogel)

Tears

2

0.15

0.21

0.05

0.02–0.19

7

0

0

0

0–0.02

14

0

0

0

0–0

23

0

0

0

0–0

Aqueous humor

2

0.001–0.005

0.001–0.005

0.003

0.001–0.005

7

0.001–0.005

0.001–0.005

0.003

0.001–0.005

14

0

0

0

0–0

23

0

0

0

0–0

Vori-Top (1% voriconazole solution)

Tears

2

3.50

3.18

3.04

0.96–8.95

Aqueous humor

2

1.52

0.31

1.42

1.25–2.07