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Table 2 Serum cobalamin and folate concentrations in lean cats and in obese cats before and after weight loss

From: Bacterial fecal microbiota is only minimally affected by a standardized weight loss plan in obese cats

AnalytesLEANOBWLOAWL
Median (Min-Max)Median (Min-Max)Median (Min-Max)
Cobalamin (pg/mL) (350–1499 pg/mL)a913 (821–973) b,d882.0 (702–928) b879.0 (571–974) d
 Mean (LL-UL)Mean (LL-UL)Mean (LL-UL)
Folate (ng/mL) (9.7–21.6 ng/mL)a18.8 (16.2–21.8)20.1 (17.7–22.9) c17.4 (15.3–19.9) c
  1. OBWL obese before weight loss, OAWL, obese after weight loss, Min minimum, Max maximum, LL-UL lower limit – upper limit
  2. The data presented here represent the cobalamin and folate serum concentrations of healthy lean cats (LEAN, n = 13) and obese cats following a 4-week adaptation period with a veterinary therapeutic food intended for weight loss and adult maintenance (OBWL, n = 17), and obese cats after a 10-week weight loss period on the same food (OAWL, n = 16)
  3. aNormal reference-range provided by the Gastrointestinal Laboratory, Texas A&M University
  4. bSignificant difference between LEAN to OBWL (and P = 0.0057 for cobalamin and P = 0.2989 for folate); Wilcoxon Mann-Whitney (cobalamin) or Student T-test after log transformation (folate)
  5. cSignificant difference between OBWL to OAWL (P = 0.8209 for cobalamin and P = 0.0321 for folate); Wilcoxon Signed Rank (cobalamin) or Paired T-test after log transformation (folate)
  6. dSignificant difference between LEAN to OAWL (P = 0.0149 for cobalamin and P = 0.6058 for folate); Wilcoxon Mann-Whitney (cobalamin) or Student T-test after log transformation (folate)