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Table 3 Clinical Trial Evaluation Schedule

From: Phase-I trial of survivin inhibition with EZN-3042 in dogs with spontaneous lymphoma

 

Time Point

Procedure

Day 0

Day 3–4

Day 7

Day 8

Lymph node biopsy (qRT-PCR, IHC) +/− PBMC collection

X

  

X

History, physical exam, response assessment

X

X

X

X

CBC, Biochemistry, PT, PTT, Urinalysis

X

X

X

 

QOL Questionnaire

X

X

X

X

Body Weight

X

X

X

X

EZN-3042 Administration

X

X

X

 
  1. IHC Immunohistochemistry. PBMC Peripheral blood mononuclear cells, CBC Complete blood count. PT Prothrombin time. APTT Activated thromboplastin time. QOL Quality of life