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Table 4 Pain and sedation scores [median (range)], and mechanical nociceptive thresholds [mean (SD)] measured prior to ovariohysterectomy (BL) and at 0.5, 1, 2, 4, 6, 8, 18 and 24 h of the postoperative period in cats treated with local infiltration of physiological saline (S), 1 mg/kg of ropivacaine (R) and ropivacaine (1 mg/kg) / meloxicam (0.2 mg/kg) (RM). All groups started with an n = 15. Animals that received rescue analgesia were removed from comparisons among treatment groups and from baseline. The actual number of animals analyzed at each time point is presented

From: Comparison of perioperative analgesia using the infiltration of the surgical site with ropivacaine alone and in combination with meloxicam in cats undergoing ovariohysterectomy

Variable

Group

Postoperative time (hours)

BL

0.5

1

2

4

6

8

12

18

24

Number of animals analyzed

S

15

15

15

13

11

11

11

11

11

11

R

15

15

15

14

14

14

14

14

14

14

RM

15

15

15

15

15

15

14

14

14

14

IVAS (0-100 mm)

S

0 (0–0)

5 (0–10)

5 (0–35)*

5 (5–35)*

10 (0–25)*

5 (0–20)*

5 (0–20)*

5 (0–15)*

5 (0–10)*

5 (0–10)*

R

0 (0–0)

5 (0–15)*

10 (0–20)*

5 (0–20)*

5 (0–15)*

5 (5–15)*

5 (0–20)*

5 (0–10)*

5 (0–10)

5 (0–10)

RM

0 (0–0)

5 (0–10)

5 (0–10)

5 (0–20)*

5 (0–35)*

5 (0–20)*

5 (0–15)*

5 (0–20)*

5 (0–10)

5 (0–15)

MCPS (0–24 point)

S

0 (0–5)

0 (0–2)

0 (0–15)

1 (0–7)

1 (0–4)

1 (0–5)

1 (0–5)

1 (0–2)

1 (0–2)

0 (0–2)

R

0 (0–3)

0 (0–2)

1 (0–7)

0.5 (0–2)

1 (0–4)

1 (0–5)

1 (0–4)

1 (0–2)

1 (0–2)

0.5 (0–2)

RM

0 (0–5)

0 (0–4)

0 (0–1)

0 (0–5)

0 (0–6)

0.5 (0–5)

1 (0–2)

1 (0–2)

0 (0–2)

0.5 (0–2)

MNT (grams)

S

211 ± 56

237 ± 92

196 ± 64

196 ± 63

188 ± 84

185 ± 51

185 ± 74

184 ± 56

183 ± 27

190 ± 28

R

288 ± 60

173 ± 87

183 ± 59

167 ± 70

142 ± 67

163 ± 61

166 ± 77

185 ± 78

180 ± 64

181 ± 64

RM

223 ± 94

280 ± 95

215 ± 93

205 ± 98

163 ± 64

156 ± 39

160 ± 56

210 ± 87

195 ± 83

185 ± 44

Sedation (0–4 point)

S

0 (0–0)

1 (0–3)*

0 (0–1)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

R

0 (0–0)

1 (0–3)*

0 (0–1)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

RM

0 (0–0)

1 (1–3)*

0 (0–1)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

  1. IVAS Interactive Visual Analogue Scale, MCPS UNESP-Botucatu Multidimensional Composite Pain Scale, MNT Mechanical Nociceptive Thresholds
  2. *Significantly different from baseline values (P < 0.05). Significantly different from S and R groups (P = 0.021–0.018)