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Table 2 Potentiation effect of serum matrix on in vitro susceptibility of gamithromycin against 19 H. parasuis isolates (n = 19) a

From: Epidemiological and PK/PD cutoff values determination and PK/PD-based dose assessment of gamithromycin against Haemophilus parasuis in piglets

Test matrix

MIC (mg/L)

MBC (mg/L)

MBC/MIC ratio

HTM

0.52 (0.23)

0.83 (0.24)

1.61

Serum

0.06 (0.02)

0.19 (0.08)

3.21

HTM/serum ratio b

8.93

4.46

–

  1. aMIC and MBC represent geometric means (SD) using 19 H. parasuis isolates
  2. bComparison of Haemophilus test medium (HTM)/serum ratio differences: P < 0.01
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BMC Veterinary Research

ISSN: 1746-6148

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