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Table 2 Values of histopathological analysis in control and methylene blue groups (MB5 and MB20)

From: Assessment of effects of methylene blue on intestinal ischemia and reperfusion in a rabbit model: hemodynamic, histological and immunohistochemical study

OrganControlMB5MB20
Duodenum4 (2.8–6.8) a1 (0.5–1.5) a3 (2–4)
Jejunum5.5 (4–6.5) a2 (0.6–2.4) a,b4 (4–6) b
Ileum4 (3–4.5) a1.25 (0.5–3.4) a,b4 (3–5) b
Lungc2.5 (1–3)2.5 (2–3)2.5 (1–3)
Neutrophils infiltrated2 (1.5–3)2(2–2.5)2 (1.8–2.8)
Livere2 (1.5–3)2 (1.6–2.5)1.5 (1–3)
Kidneyf2.5 (2–3)2.75 (2.5–3)2.5 (1.9–2.6)
  1. Legend: Data are expressed as median (P25–P75)
  2. a. Significant difference (P < 0.05) between MB5 and control group
  3. b. Significant difference (p < 0.05) between MB5 and MB20
  4. Scoring system followed for lung, neutrophils infiltrate, liver and kidney (more details in methods section):
  5. c0 (absence of lesions). 1 slight (focal lesions), 2 moderate (multifocal lesions), and 3 severe (diffuse lesions)
  6. d1 occasional (0–5 cells), 2 slight (6–15 cells), 3 moderate (16–30 cells), and 4 severe (> 30 cells)
  7. e0 (normal), 1 (slight), 2 (moderate); 3 (severe) to 4 (very severe)
  8. f0 (normal), 1 (slight; 0–50 vacuoles), 2 (moderate; 50–-100) and 3 (severe; > 100)