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Fig. 3 | BMC Veterinary Research

Fig. 3

From: Enolase and dipeptidyl peptidase IV protein sub-unit vaccines are not protective against a lethal Streptococcus suis serotype 2 challenge in a mouse model of infection

Fig. 3

Titers of anti-Enolase antibody isotypes of mice immunized with rEnolase in combination with 4 adjuvants. Two 50 μg doses of rSsEno adjuvanted in Quil-A®, Polygen™, Stimune® or Montanide™ ISA 50 V2 were administered to mice. A control group (non-immunized) received 100 μL of phosphate-buffered saline. Isotypes were detected in sera twelve days after the first (Dose 1) and the second (Dose 2) vaccination. Data are expressed as mean ± standard error of the mean. * (p < 0.05) indicates a significant difference between non-immunized and dose 1. # (p < 0.05) indicates a significant difference between dose 1 and dose 2 and a (p < 0.05) between treated groups (adjuvants) for the second immunization (Dose 2)

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