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Fig. 7 | BMC Veterinary Research

Fig. 7

From: Proinflammatory cytokines and lipopolysaccharides up regulate MMP-3 and MMP-13 production in Asian elephant (Elephas maximus) chondrocytes: attenuation by anti-arthritic agents

Fig. 7

Activation of the MAPK pathway in ELACs by IL-1β combined with OSM. ELACs were stimulated by the combination of IL-1β (2.5 ng/mL) and OSM (2.5 ng/mL) at the indicated time points. Cell lysates were immunoblotted to investigate the total and phosphorylated molecular forms, which indicated an active MAPK pathway. Immunoblots are represented in (a) and bar graphs (b) show the proportion between the band intensities of phosphorylated p38, ERK, and JNK over their total forms. Results are presented as mean ± SEM. * signifies statistical significance compared with control (*p < 0.05)

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