Table 2 Baseline values and characteristics of dogs
| Â | MMVD | p-value | Healthy | p-value | ||
|---|---|---|---|---|---|---|
CON | CPB | CON | CPB | |||
Total number | 9 | 10 | nd | 8 | 9 | nd |
Sex (M/F) | 5/4 | 6/4 | nd | 4/4 | 5/4 | nd |
Age, years | 11.2 (7.9–13.7) | 10.5 (8.1–12.5) | 0.45 | 9.9 (1.6–12.9) | 10.3 (8.1–13.0) | 0.79 |
Breed (Beagle/Miniature Schnauzer) | 8/1 | 9/1 | nd | 7/1 | 8/1 | nd |
Physical examination variables | ||||||
 Body weight, kg | 10.4 (7.43–12.94) | 9.8 (6.52–12.69) | 0.55 | 11.0 (7.84–13.58) | 12.0 (7.53–15.94) | 0.35 |
 BCS | 5.2 (4–6) | 5.0 (4–6) | 0.48 | 5.8 (5–7) | 5.6 (5–6) | 0.55 |
 Heart rate | 118 (95–140) | 112 (95–153) | 0.57 | 120 (93–152) | 120 (87–156) | 0.99 |
 SAP (mmHg) | 190.8 (150–219) | 171.0 (133–218) | 0.10 | 171.2 (146–211) | 191.9 (164–217) | 0.04 |
 DAP (mmHg) | 104.9 (91–131) | 106.2 (77–133) | 0.84 | 99.5 (77–131) | 114.3 (73–139) | 0.11 |
 Heart murmur grade (1/2/3/4) | 0/4/4/1 | 1/3/5/1 | 0.46 | 0/0/0/0 | 0/0/0/0 | nd |
 ACVIM stages (B1/B2) | 7/2 | 8/2 | nd | 0/0 | 0/0 | nd |
Echocardiogram variables | ||||||
 LAD (cm) | 1.97 (1.47–2.58) | 2.04 (1.39–2.67) | 0.70 | 1.87 (1.46–2.3) | 1.93 (1.37–2.26) | 0.70 |
 LA/Ao | 1.16 (0.91–1.56) | 1.22 (1.1–165) | 0.54 | 1.00 (0.77–1.16) | 1.07 (0.93–1.24) | 0.28 |
 LVD (cm) | 3.11 (2.57–3.57) | 3.17 (2.62–3.59) | 0.69 | 2.92 (2.54–3.38) | 3.00 (2.39–3.49) | 0.64 |
 MVR (m/s) | 5.50 (5.03–6.28) | 5.75 (5.40–6.32) | 0.14 | nd | nd | nd |
 EF (%) | 74 (67–86) | 70 (60–81) | 0.14 | 70 (63–83) | 68 (59–74) | 0.50 |
 MR (none or trace/mild/moderate/severe) | 0/2/5/2 | 0/0/5/5 | nd | 7/1/0/0 | 8/1/0/0 | nd |