Skip to main content

Table 2 Baseline values and characteristics of dogs

From: Dietary intervention reduces left atrial enlargement in dogs with early preclinical myxomatous mitral valve disease: a blinded randomized controlled study in 36 dogs

 MMVDp-valueHealthyp-value
CONCPBCONCPB
Total number910nd89nd
Sex (M/F)5/46/4nd4/45/4nd
Age, years11.2 (7.9–13.7)10.5 (8.1–12.5)0.459.9 (1.6–12.9)10.3 (8.1–13.0)0.79
Breed (Beagle/Miniature Schnauzer)8/19/1nd7/18/1nd
Physical examination variables
 Body weight, kg10.4 (7.43–12.94)9.8 (6.52–12.69)0.5511.0 (7.84–13.58)12.0 (7.53–15.94)0.35
 BCS5.2 (4–6)5.0 (4–6)0.485.8 (5–7)5.6 (5–6)0.55
 Heart rate118 (95–140)112 (95–153)0.57120 (93–152)120 (87–156)0.99
 SAP (mmHg)190.8 (150–219)171.0 (133–218)0.10171.2 (146–211)191.9 (164–217)0.04
 DAP (mmHg)104.9 (91–131)106.2 (77–133)0.8499.5 (77–131)114.3 (73–139)0.11
 Heart murmur grade (1/2/3/4)0/4/4/11/3/5/10.460/0/0/00/0/0/0nd
 ACVIM stages (B1/B2)7/28/2nd0/00/0nd
Echocardiogram variables
 LAD (cm)1.97 (1.47–2.58)2.04 (1.39–2.67)0.701.87 (1.46–2.3)1.93 (1.37–2.26)0.70
 LA/Ao1.16 (0.91–1.56)1.22 (1.1–165)0.541.00 (0.77–1.16)1.07 (0.93–1.24)0.28
 LVD (cm)3.11 (2.57–3.57)3.17 (2.62–3.59)0.692.92 (2.54–3.38)3.00 (2.39–3.49)0.64
 MVR (m/s)5.50 (5.03–6.28)5.75 (5.40–6.32)0.14ndndnd
 EF (%)74 (67–86)70 (60–81)0.1470 (63–83)68 (59–74)0.50
 MR (none or trace/mild/moderate/severe)0/2/5/20/0/5/5nd7/1/0/08/1/0/0nd
  1. MMVD, myxomatous mitral valve disease; CON, control diet; CPB, cardiac protection blend; BCS, body condition score; LAD, left atrial diameter; LA/Ao, left atrial to aortic root ratio; LVD, left ventricular diameter; MVR, mitral regurgitation velocity; EF, ejection fraction; MR, mitral regurgitation; SAP, systolic arterial pressure; DAP, diastolic arterial pressure; ACVIM, American College of Veterinary Internal Medicine; nd, not detectable or determined. One MMVD dog in the control diet group developed lymphoma after three months and was subsequently removed from the study. Continuous variables are reported as mean (range). P values were calculated using t-test