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Table 1 Results of PPR experimental infection on goats according five severity criteria

From: Peste des petits ruminants pathogenesis on experimental infected goats by the Moroccan 2015 isolate

Group

Animal

Mortality score

Clinical score

Tissue virus load score

Hyperthermia duration (days)

Swabs virus load score

Severity score

I

1

2

13

2.2

6

1.6

82.2

2

1

15

2.8

8

2

91.4

II

3

2

14

2.7

9

1.9

94

4

3

17

3.7

7

2.3

110.4

  1. Group I was infected by cell virus suspension with a titer of 6.2 logTCID50/ml. Group II was infected by infectious mashed tissue (lung and mesenteric node). both from the same isolate. For each individual goat. a severity score was calculated. We evaluated five criteria by significance: 1) Mortality. 2); Clinical scoring; 3) Viral load in post mortem tissue; 4) Hyperthermia duration; 5) Viral load in swabs (number of positive and cycle threshold (Ct) values). Each criteria has a coefficient of significance (5 point for criteria 1 to 1 point for criteria 5). The severity score is a cumulative value of each criteria score. Previously multiplied by the coefficient of significance
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BMC Veterinary Research

ISSN: 1746-6148

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