Table 1 Test results for each marker and the results of ROC analysis
From: Simultaneous evaluation of diagnostic marker utility for enzootic bovine leukosis
Marker*1 | Unit | EBL cattle*2 | Non-EBL cattle*3, *4 | Thresholds*5 | AUC (95%CI)*6 | Se (%)*7 | Sp (%)*8 | ||
|---|---|---|---|---|---|---|---|---|---|
Mean | Median (95 percentile) | Mean | Median (95 percentile) | ||||||
TK | Du/L | 2805.6 | 2321 (97.2–10,031.0) | 23.73 | 12.5 (−70.475–162.8) | 99.7 | 0.98 (0.96–1.00) | 97.1 | 97.0 |
LDH2 | IU/L | 1084.1 | 936.9 (169.5–2602.3) | 397.8 | 288 (146.2–1244.4) | 460.6 | 0.87 (0.83–0.91) | 82.8 | 81.7 |
Total LDH | IU/L | 3743 | 3038 (812.3–10,010.1) | 1695.1 | 1002 (544.0–7428.8) | 1389 | 0.85 (0.81–0.89) | 87.5 | 75.8 |
LDH3 | IU/L | 693.9 | 634.4 (86.0–1735.7) | 267.2 | 168.2 (75.2–1048.8) | 283.7 | 0.85 (0.80–0.89) | 82.2 | 79.7 |
TNFR II/I | – | 0.93 | 0.68 (0.06–4.15) | 0.26 | 0.17 (0.09–0.80) | 0.3 | 0.85 (0.79–0.90) | 81.7 | 81.8 |
LDH1 | IU/L | 1100.3 | 920.7 (335.6–2708.6) | 602.7 | 438.5 (270.2–1843.5) | 564.5 | 0.83 (0.79–0.87) | 82.2 | 75.1 |
LDH4 | IU/L | 485.5 | 168.6 (24.9–1330.9) | 143.6 | 63.9 (20.5–829.0) | 91.6 | 0.77 (0.72–0.82) | 79.3 | 74.6 |
No. of lymphocytes | 102/ul | 316.8 | 108 (16.7–2112.0) | 46.4 | 34 (13.0–138.3) | 75.5 | 0.76 (0.70–0.81) | 61.3 | 73.2 |
PVL | copies/10 ng DNA | 3289.8 | 1969.3 (28.3–16,224.0) | 1536.6 | 779.9 (0.0–5729.7) | 3433.1 | 0.69 (0.63–0.75) | 51.9 | 72.4 |
LDH5 | IU/L | 289.94 | 66.45 (9.7–1881.9) | 285.76 | 41.5 (10.5–2574.0) | 54.5 | 0.6 (0.54–0.66) | 60.9 | 62.9 |