Fig. 3
From: Composite lymphoma of concurrent T zone lymphoma and large cell B cell lymphoma in a dog
Sequencing-based clonality test results, analysed and visualized by ARResT/Interrogate (http://arrest.tools/interrogate), from replicate samples diagnosed as TZL (a-c), ‘composite’ TZL and LBCL (d-f), and from a reactive lymph node of a different patient (g-i). X-axis: amino acid length of junctional region, double bars per junction length represent replicates; Y-axis: abundance of clones. The 100 most abundant clones are displayed as colored slices of a bar, less abundant clones are grey. Identical colors within one subfigure represent identical clonotypes. Dominant clones in a polyclonal background are visible for the TRB and TRG loci in the TZL sample, and in the TZL/LBCL sample. For the IGH locus, polyclonal results were obtained for the TZL sample and a clonal result for the TZL/LBCL sample. The reactive lymph node control sample gave polyclonal results for all loci (g-i). Bars with colored arrows are highlighted in Fig. 4