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Table 1 Univariable mixed logistic regression models for canine leptospirosis PCR tests in the United States (2009–2016)

From: A cross-sectional study of environmental, dog, and human-related risk factors for positive canine leptospirosis PCR test results in the United States, 2009 to 2016

Variable

N (%)

Odds Ratio (95% CI)

p-value

Dog age (years)

< 0.001

 0–4

10,612 (27.2)

Reference

 

 5–7

9503 (24.3)

0.72 (0.64, 0.80)

< 0.001

 8–10

10,176 (26.1)

0.49 (0.43, 0.55)

< 0.001

  > 10

8752 (22.4)

0.34 (0.30, 0.40)

< 0.001

Dog sex

< 0.001

 Female

20,299 (51.3)

Reference

 

 Male

19,253 (48.7)

1.31 (1.20, 1.43)

 

Season test performed

< 0.001

 Fall

7604 (18.9)

Reference

 

 Winter

10,405 (25.9)

0.78 (0.70, 0.88)

< 0.001

 Spring

9402 (23.4)

0.47 (0.41, 0.54)

< 0.001

 Summer

12,707 (31.7)

0.63 (0.56, 0.72)

< 0.001

Year test performed

< 0.001

 2009

4.4% (3.4, 5.6%)1

Reference

 

 2010

2.6% (2.0, 3.2%)1

0.57 (0.40, 0.81)

0.001

 2011

2.6% (2.0, 3.2%)1

0.57 (0.40, 0.80)

0.001

 2012

3.8% (3.2, 4.4%)1

0.86 (0.63, 1.17)

0.333

 2013

7.7% (6.9, 8.5%)1

1.81 (1.36, 2.40)

< 0.001

 2014

7.5% (6.9, 8.2%)1

1.73 (1.31, 2.28)

< 0.001

 2015

6.1% (5.6, 6.6%)1

1.35 (1.03, 1.78)

0.031

 2016

5.0% (4.6, 5.4%)1

1.11 (0.84, 1.46)

0.446

County urban influence code2

0.013

 Non-urban

3337 (8.3)

Reference

 

 Urban

36,781 (91.7)

1.31 (1.06, 1.61)

 

County dog density (dogs/mi2)2

0.013

 0–50

8788 (21.9)

Reference

 

 51–150

11,059 (27.6)

1.17 (0.98, 1.39)

0.088

 151–350

9956 (24.8)

1.41 (1.15, 1.72)

0.001

  > 350

10,315 (25.7)

1.32 (1.04, 1.64)

0.020

Region2

0.010

 Midwest

9536 (23.8)

Reference

 

 Southwest

4994 (12.5)

0.89 (0.57, 1.40)

0.624

 West

9230 (23.0)

0.52 (0.37, 0.75)

< 0.001

 Southeast

8032 (20.0)

0.65 (0.48, 0.87)

0.003

 Northeast

8326 (20.8)

0.73 (0.53, 0.99)

0.046

State climate division Palmer Drought Severity Index2,3

< 0.001

  ≤ 0 (dry conditions)

20,852 (52.0)

Reference

 

  > 0 (wet conditions)

19,266 (48.0)

1.24 (1.12, 1.37)

 

State climate division precipitation (centimeters)2,3

< 0.001

 0–2.5

6550 (16.3)

Reference

 

 2.6–7.6

13,764 (34.3)

1.33 (1.14, 1.56)

< 0.001

 7.7–12.7

12,327 (30.7)

1.44 (1.22, 1.70)

< 0.001

  > 12.7

7477 (18.6)

1.37 (1.15, 1.64)

0.001

State climate division temperature (°C)2,3

0.001

  ≤ 4

6795 (16.9)

Reference

 

 5–13

10,460 (26.1)

1.24 (1.07, 1.43)

0.003

 14–21

12,550 (31.3)

1.05 (0.91, 1.21)

0.496

  > 21

10,313 (25.7)

0.99 (0.85, 1.16)

0.914

County percent of adults with a bachelors degree or higher2

0.641

  < 50%

36,634 (91.3)

Reference

 

  ≥ 50%

3484 (8.7)

0.97 (0.73, 1.29)

 

County median household income (USD)2

0.871

  < $50,000

6126 (15.3)

Reference

 

 $50,000–$74,999

23,778 (59.3)

0.97 (0.81, 1.16)

0.731

 $75,000–$99,999

8426 (21.0)

0.96 (0.76, 1.21)

0.729

  ≥ $100,000

1788 (4.5)

1.11 (0.75, 1.66)

0.594

County water cover percentage2

0.180

  ≤ 1%

5929 (14.8)

Reference

 

 1.01–4%

13,638 (34.0)

1.01 (0.83, 1.23)

0.904

 4.01–15%

10,483 (26.1)

1.22 (0.97, 1.53)

0.086

  > 15%

10,068 (25.1)

1.13 (0.89, 1.43)

0.334

  1. 1Test-positive proportion and 95% CI provided, as a data governance agreement precluded inclusion of test numbers by year
  2. 2Location based on veterinary facility that submitted sample for testing
  3. 3Climate data for month and year test was performed