Haemostatic, fibrinolytic and inflammatory profiles in West Highland white terriers with canine idiopathic pulmonary fibrosis and controls

Table 4 Haemostatic data from CIPF and CTRL WHWTs

Variable	n	CIPF WHWTS	n	CTRL WHWTs	P-value	RI^a
PT (sec)	13	7.2 (6.4–8.7)	19	7.2 (6.3–12.7)	0.48	5.7–8.1
APTT (sec)	12	12.1 (10.8–13.8)	16	11.4 (10.3–12.7)	0.028	10.0–14.3
Fibrinogen (g/L)	13	3.7 (1.9–8.5)	19	2.8 (1.6–5.1)	0.067	1.3–3.1
D-dimers (uGu/mL)	10	0.25 (0.07–0.32)	18	0.19 (0.09–0.30)	0.38	0.02–0.65
AT-III (%)	10	110 (82–215)	18	142 (96–171)	0.093	108–128
Protein S (%)	11	118 (23–274)	17	120 (0–496)	0.91	74.4–160.5
Protein C (%)	11	103 (72–286)	17	93 (10–304)	0.38	75.5–118.9
FXa (UI/mL)	10	0.10 (0.04–0.70)	18	0.16 (0.09–0.20)	0.29	0.04–0.26
APCR (sec)	11	25.6 (21.9–27.7)	17	26.8 (23.8–64.4)	0.066	20.0–30.0

Abbreviations: CIPF canine idiopathic pulmonary fibrosis, WHWTs West Highland white terriers, CTRL control, RI reference intervals, PT prothrombin time, APTT activated partial thromboplastine time, AT-III antithrombin III activity, FXa anti-factor Xa activity, APCR activated protein C ratio
^aLaboratory-internal reference intervals established from 56 clinically healthy dogs (Bauer N [13])

ISSN: 1746-6148