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Table 4 Haemostatic data from CIPF and CTRL WHWTs

From: Haemostatic, fibrinolytic and inflammatory profiles in West Highland white terriers with canine idiopathic pulmonary fibrosis and controls

Variable n CIPF WHWTS n CTRL WHWTs P-value RIa
PT (sec) 13 7.2 (6.4–8.7) 19 7.2 (6.3–12.7) 0.48 5.7–8.1
APTT (sec) 12 12.1 (10.8–13.8) 16 11.4 (10.3–12.7) 0.028 10.0–14.3
Fibrinogen (g/L) 13 3.7 (1.9–8.5) 19 2.8 (1.6–5.1) 0.067 1.3–3.1
D-dimers (uGu/mL) 10 0.25 (0.07–0.32) 18 0.19 (0.09–0.30) 0.38 0.02–0.65
AT-III (%) 10 110 (82–215) 18 142 (96–171) 0.093 108–128
Protein S (%) 11 118 (23–274) 17 120 (0–496) 0.91 74.4–160.5
Protein C (%) 11 103 (72–286) 17 93 (10–304) 0.38 75.5–118.9
FXa (UI/mL) 10 0.10 (0.04–0.70) 18 0.16 (0.09–0.20) 0.29 0.04–0.26
APCR (sec) 11 25.6 (21.9–27.7) 17 26.8 (23.8–64.4) 0.066 20.0–30.0
  1. Abbreviations: CIPF canine idiopathic pulmonary fibrosis, WHWTs West Highland white terriers, CTRL control, RI reference intervals, PT prothrombin time, APTT activated partial thromboplastine time, AT-III antithrombin III activity, FXa anti-factor Xa activity, APCR activated protein C ratio
  2. aLaboratory-internal reference intervals established from 56 clinically healthy dogs (Bauer N [13])