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Fig. 4 | BMC Veterinary Research

Fig. 4

From: Bacitracin resistance and enhanced virulence of Streptococcus suis via a novel efflux pump

Fig. 4

Bacterial competitive colonization and virulence analysis in vivo. a The competitive test was carried out to compare the colonization between wild-type and mutant strains in mouse infection model. The bacterial loads of mutant strains were decreased by approximately two- or three-fold in comparison with the wild-type strain in blood after intraperitoneal challenge for 10 h, ** P < 0.01 and *** P < 0.001. b Survival curves of BALB/c mice infected with wild-type or mutant strains. Six-week-old female BALB/c mice were segregated into three groups and inoculated i.p. with 2.6 × 107 cells/mouse. Mice infected with the vehicle solution (PBS) were used as controls and survival was monitored over a 7-d period. Data are expressed as the mean percentage of live animals in each group (n = 11), * P < 0.05

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