Table 9 Clinical trials carried out with mesenchymal stem cells in feline asthma
From: Mesenchymal stem cells therapy in companion animals: useful for immune-mediated diseases?
Species (number) | Treatment | Results | Conclusion | Reference |
|---|---|---|---|---|
Cat (6) Acute asthma | Five IV allogeneic ASCs (varied between 2 × 106 and 1 x 107per cat) | Decreased in: airway eosinophilia, hyper-responsiveness and airway remodeling | ASCs therapy had a positive effect on airway remodeling | [71] |
Cat (9) Chronic asthma | Six IV allogeneic ASCs (with range amplitude of 0.36–2.5 × 107 MSCs/infusion) | Decreased in airway remodeling | [79] |