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Table 6 Conventional and immunomodulatory therapeutic approach to inflammatory bowel disease

From: Mesenchymal stem cells therapy in companion animals: useful for immune-mediated diseases?

 

Inflammatory Bowel Disease

First line approach

Sequential treatment trials of parasiticides, an exclusion diet, and antibacterials to exclude known causes of inflammation before the immunosuppressive treatment [63].

Corticosteroids

Oral prednisolone (1 mg/kg BID) [63, 64, 68].

Other immunosuppressive agents

Azathioprine (frequently used in dogs when IBD cannot be effectively managed with glucocorticoids) or cyclosporine (inhibits the production of IL-2) [63, 64, 68].