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Table 2 Structural equation model statistical output showing host characteristics predicting serological exposure status for co-infecting pathogens (except ClinL), and the covariance among pathogens (including ClinL), in domestic dogs. The covariances E. canis, A. platys, Hepatozoon spp. and M. haemocanis were PCR based diagnosed. In all cases, except age, variables are binomial (0 or 1) with 1 equal to male, outside, ectoparasites controlled, pedigree and positive pathogen status

From: Associations between clinical canine leishmaniosis and multiple vector-borne co-infections: a case-control serological study

 

Standardised coefficient/covariance

z-value

P-value

E. canis/E. ewingii serology

 Age

−0.081

−0.908

0.364

 Sex

−0.015

− 0.143

0.886

 Lifestyle

0.059

0.515

0.606

 Ectoparasite prevention

−0.041

− 0.336

0.737

 Pedigree

0.015

0.142

0.887

A. phagocytophilum/A. platys serology

 Age

−0.035

−0.415

0.678

 Sex

0.014

0.103

0.918

 Lifestyle

−0.037

− 0.363

0.717

 Ectoparasite prevention

−0.162

−1.532

0.126

 Pedigree

−0.111

−0.861

0.389

Covariances

E. canis/E. ewingii ~~ ClinL

0.229

2.453

0.014

A. phagocytophilum/A. platys ~~ ClinL

0.183

1.654

0.098*

E. canis/E. ewingii ~~ A. phagocytophilum/A. platys

0.180

1.443

0.149

E. canis/E. ewingii ~~ E. canis

0.317

2.164

0.030

E. canis/E. ewingii ~~ A. platys

0.009

0.092

0.926

E. canis/E. ewingii ~~ Hepatozoon spp.

0.068

0.747

0.455

E. canis/E. ewingii ~~ M. haemocanis

0.099

1.015

0.310

A. phagocytophilum/A. platys ~~ E. canis

−0.015

−0.358

0.721

A. phagocytophilum/A. platys ~~ A. platys

0.349

1.290

0.197

A. phagocytophilum/A. platys ~~ Hepatozoon spp.

−0.106

−1.167

0.243

A. phagocytophilum/A. platys ~~ M. haemocanis

0.000

−0.005

0.996

  1. Significant relationships (P < 0.05) denoted by bold font and trending relationships (P < 0.1) denoted by *
  2. Abbreviations: VBP Vector-borne pathogen, ClinL Clinical leishmaniosis, E. canis Ehrlichia canis, E. ewingii Ehrlichia ewingii, A. phagocytophilum Anaplasma phagocytophilum, A. platys. Anaplasma platys, M. haemocanis Mycoplasma haemocanis