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Fig. 3 | BMC Veterinary Research

Fig. 3

From: Local immune and microbiological responses to mucosal administration of a Liposome-TLR agonist immunotherapeutic in dogs

Fig. 3

Macrophages activated by LTC exhibit increased bactericidal activity. Monocyte-derived macrophages (MDM) from 3 dogs were treated with LTC for 24 h, after which the cells were infected with a canine methicillin-resistant strain of S. pseudointermedius at an MOI of 5 and killing of internalized bacteria was assessed by comparing CFU from macrophage cultures in untreated vs. LTC treated cells. Comparisons between groups were done using ANOVA, followed by Tukey multiple means post-test. Analyses were performed using Prism 8 software (GraphPad, La Jolla, CA). For all analyses, statistical significance was determined if p ≤ 0.05

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