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Table 1 Inhibitory effects of T-705 against CDV replication in different cell lines

From: Antiviral efficacy of favipiravir against canine distemper virus infection in vitro

Virus

CC50 ± SD (μg/ml)a

IC50 ± SD (μg/ml)a

SI b

Vero

DH82

Vero

DH82

Vero

DH82

CDV-3

> 1250

> 1250

25.20 ± 2.69

33.54 ± 1.20

> 49.60

> 37.27

CDV-11

> 1250

> 1250

7.05 ± 1.87

16.97 ± 3.35

> 177.30

> 73.66

  1. aDetermined from 3 independent experiments
  2. bSelectivity index (SI) calculated as CC50/IC50